Inhibitors | Comment | Organism | Structure |
---|---|---|---|
isovitexin | interacts with enzyme residues Glu121, Leu83, Ala84, Pro140, Ile141, His120, Ala136, Leu116, Ala139, and Leu137, binding structure analysis, and modelling, overview | Homo sapiens | |
additional information | Ficus deltoidea leaf extract inhibits matrix metalloproteinase-2, 8 and 9, molecular docking, molecular dynamics, molecular dynamic simulation analysis, overview. Computational docking analysis reveals that vitexin and isovitexin binds to the active site of the three tested MMPs | Homo sapiens | |
N-isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid | NNGH | Homo sapiens | |
vitexin | interacts with enzyme residues Leu83, Ala84, His130, Pro140, Ala139, Met138, Ala, 136, Leu137, Thr143, Tyr142, Val117, His120, and Ile141, binding structure analysis, and modelling, overview | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | zinc-dependent metalloproteinase | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P08253 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Homo sapiens | - |
EAhy 926 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
matrix metalloproteinase-2 | - |
Homo sapiens |
MMP-2 | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Homo sapiens |